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Slowing down platelet aggregation: The Infuence of Herbal Medicine on Platelet
Dr. Hyun Kim
Clinical Pharmacogenomics Service · Boston Children’s hospital
April 2015 · Seminars in Thrombosis and Hemostasis 41(03) DOI:10.1055/s-0035-1549089
Source · PubMed
“Platelet activation and aggregation play a central role in hemostasis and thrombosis. Herbal medicines have been traditionally used in the management of CVD and can play a role in modifying CVD progression, particularly in platelet function, and have the potential of altering platelet function tests, as well as some coagulation parameters. Herbal medicines, such as feverfew, garlic, ginger, ginseng, motherwort, St John’s wort, and willow bark, were found to reduce platelet for Andrographis, feverfew, garlic, ginger, Ginkgo, ginseng, hawthorn, horse chestnut, and turmeric. In addition, cranberry, danshen, dong quai, Ginkgo, ginseng, green tea, and St John’s wort were found to have potential interactions with
warfarin. Furthermore, St John’s wort interacted with clopidogrel and danshen with aspirin. Therefore, repeat testing of platelet function and coagulation studies, particularly for patients on warfarin therapy, may be required after exclusion of herbal medicines that could have possibly affected initial test results. Thieme
Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.”
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